A high purity HPLC solvent. For improved reproducibility and detection sensitivity of the chromatography, the stability of the analyte, stability of the mobile phase, clogging in the line and filter, sensitivity and stability of the detector have been considered, and the product has guaranteed quality with respect to change in refractive index due to water, peroxides, nonvolatile matters, or impurities in the solvent; UV absorption; and fluorescent substances; etc.Filtration of the product through a 0.45-micrometer membrane filter in the final process results in high reproducibility of data and extension of column life.